Search results for "Mechanistic modeling; process devel…"
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Mechanistic Modeling of Preparative Ion-Exchange Chromatography
By Anurag Rathore, Vijesh Kumar
Among the various downstream processing unit operations that are used for purification of biotech products, chromatography is uniquely capable of providing resolu…
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Using Digital Twins to Model Process Chromatography
Mechanistic models provide process understanding for developing robust manufacturing processes and for scale up and tech transfer.
By Jennifer Markarian
A digital twin is a model of a proces…
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Insider Recommendations for Getting Started with Mechanistic Modeling of Chromatography
Insider Recommendations for Getting Started with Mechanistic Modeling of Chromatography
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Gunnar Malmquist, Senior Principal Scie…
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Top Tips for Successful Development of Antibody Chromatography Processes
In this interview, Jakob Liderfelt, Product Manager at Cytiva, discusses main challenges faced during chromatography process development for mAbs and mAb variants such as fragments and bispecific a…
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See a chromatography modeling software in action
Mechanistic models use computer simulations to decrease the number of experiments you need during process development.
The simulations are based on known physiochemical phenomena involved in ch…
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Sign-up to join Chromatography Virtual Summit 2022
Latest advancements in chromatography process development.
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Virtual event 15–17 November 2022
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Chromatography for the Diversified Antibody Pipeline
CytivaVideo
In this video, Eva Heldin, Section Manager of Antibody Application in R&D at Cytiva is interviewed by BioPharm International and shares what antibody therapies are in the pipelin…
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Create Digital Twins of your Chromatography Processes
Mechanistic models make it possible to create computer simulations of chromatograms. The simulations, are based on physiochemical phenomena known to occur in chromatography. The benefit of a …
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Chromatography Process Development Going Smarter
In this presentation, Henrik Ihre, business leader at Cytiva, outlines some industry drivers to go smarter and faster in process development as well as insights on the evolution of process…
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Rethinking ion exchange chromatography modeling
In the early days of modeling, mechanistic models for ion exchange chromatography were mostly based on stoichiometric equations. A new adsorption isotherm class was introduced in 2021: the co…